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One Substance, One Assessment (OSOA) is a European Union initiative designed to ensure that each chemical substance is assessed only once for hazard and risk, with that assessment shared across all EU regulatory frameworks. 

Both QSARs and Read-Across are widely accepted tools in animal-free safety assessment.  Yet in cosmetic safety discussions, this question keeps coming up:  𝗦𝗵𝗼𝘂𝗹𝗱 𝘄𝗲 𝘁𝗿𝘂𝘀𝘁 𝗤𝗦𝗔𝗥𝘀 𝗼𝗿 𝗥𝗲𝗮𝗱-𝗔𝗰𝗿𝗼𝘀𝘀?