Artificial intelligence is playing an increasing role in drug discovery, chemical research and toxicology. However, many machine learning models still work as “black boxes”, making their predictions difficult to interpret and sometimes difficult to use in industrial or regulatory contexts.

New Approach Methodologies, or NAMs, are increasingly seen as critical to phasing out animal testing. These non-animal methods have the potential to support more ethical and human-relevant science.

For too long, safety came after innovation: invent, produce, test and fix. Safe and Sustainable by Design NAMs support a different approach by helping predict risks before a product even exists.